CF Montreal – DC United: Home team win or draw
Charlotte FC – Real Salt Lake: Home team to win
Inter Miami – LA Galaxy: Home team to win
New England Rev – Los Angeles FC: Home or away team to win (no draw)
NY Red Bulls – Philadelphia Un: Away team win or draw
Orlando City – Sporting Kansas: Home team to win
Toronto – Columbus Crew: Away team win or draw
Austin FC – Dallas: Home team win or draw
Chicago Fire – St. Louis City: Home team to win
Minnesota Utd – Seattle Sounders: Draw
Colorado Rapids – Atlanta Utd: Home team win or draw
Portland Timbers – FC Cincinnati: Home or away team to win (no draw)
New York City – Nashville SC: Home or away team to win (no draw)
| H | C | L | Teams | 1% | X% | 2% | T |
|---|---|---|---|---|---|---|---|
| 00:30 | Usa1 | USA – MLS | CF Montreal – DC United | 46 | 26 | 28 | 1X |
| 00:30 | Usa1 | USA – MLS | Charlotte FC – Real Salt Lake | 56 | 17 | 27 | 1 |
| 00:30 | Usa1 | USA – MLS | Inter Miami – LA Galaxy | 43 | 30 | 27 | 1 |
| 00:30 | Usa1 | USA – MLS | New England Rev – Los Angeles FC | 33 | 32 | 35 | 12 |
| 00:30 | Usa1 | USA – MLS | NY Red Bulls – Philadelphia Un | 33 | 20 | 47 | X2 |
| 00:30 | Usa1 | USA – MLS | Orlando City – Sporting Kansas | 58 | 23 | 19 | 1 |
| 00:30 | Usa1 | USA – MLS | Toronto – Columbus Crew | 24 | 33 | 43 | X2 |
| 01:30 | Usa1 | USA – MLS | Austin FC – Dallas | 34 | 41 | 25 | 1X |
| 01:30 | Usa1 | USA – MLS | Chicago Fire – St. Louis City | 42 | 31 | 27 | 1 |
| 01:30 | Usa1 | USA – MLS | Minnesota Utd – Seattle Sounders | 38 | 31 | 31 | X |
| 02:30 | Usa1 | USA – MLS | Colorado Rapids – Atlanta Utd | 46 | 30 | 24 | 1X |
| 03:30 | Usa1 | USA – MLS | Portland Timbers – FC Cincinnati | 34 | 31 | 35 | 12 |
| 22:00 | Usa1 | USA – MLS | New York City – Nashville SC | 44 | 14 | 42 | 12 |
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